The Universidad Nacional de Entre Ríos was founded in 1973. Since its creation, the University has experienced steady growth and has firmly established its educational and scientific mission. This has been achieved with the constant collaboration of its professors, researchers, students, employees and the steadfast support of the society that sustains it. The Faculty of Engineering is proud to have been the pioneer in granting in 1985 the first Bioengineering university degree in Argentina. It was pioneer not only in Argentina but also in South America, and shares with Mexico the privilege of having being the first in Latin America.

The Faculty of Engineering undertakes extensive research and extension work. Its Research Groups transfer to the socio-economic community their knowledge and research results in science and technology. Their ample research areas include Computational Biomechanics, Biomechanics of the Human Gait, Computational Materials, Biology, Electronic Microscopy, Cybernetics, Artificial Intelligence, Advanced Calculus, Engineering Rehabilitation, Bioimplants, Signal Analysis and nonlinear Dynamics, Clinical Engineering, Telemedicine, Nanotechnology, Bioelectricity and the dissemination of Science .

The Faculty of Engineering is located in the town of Oro Verde at just 10 km from the city of Parana, capital of the Province of Entre Rios. Oro Verde is a small town with an economy based on agriculture and with a lively university community which has promoted the improvement of the town's housing structure. To the South of Oro Verde, a settlement of Russian-German immigrants from the Volga River originated the community presently living in the area.

The city of Paraná has a population of approximately 300,000 people and is the seat of the Province of Entre Rios government. In addition, an industrial park with first class industries is located in Paraná and it is a tourist center much visited by Argentinians from other regions. The city stands on cliffs overlooking the Parana River, one of the longest rivers with highest flow rate in the world. In the mid-nineteenth century, Paraná was the capital of the so-called Confederación Argentina, which excluded the province of Buenos Aires. This fact endows the city with a very strong historical significance. The town of Paraná is connected to the Province of Santa Fe through a tunnel built under the river Paraná, the Begnis Uranga-Silvestre Underwater Tunnel. This tunnel was given the names of the politicians responsible for the building of the monumental piece of engineering.

The underwater tunnel and a highway of some 20 km join Parana to the city of Santa Fe, another important city, capital of the neighboring province of Santa Fe. Santa Fe has about 500,000 inhabitants and was founded in 1573 by the Spaniard Don Juan de Garay. Today it houses the Santa Fe government center. It is a major industrial location and has important university, scientific and technological developments. Santa Fe is known for being home to major events and conferences and has the title of birthplace of the Constitution, enacted in 1853 and renewed several times. Until today Constitution renewals have always taken place in Santa Fe.